abstract：BACKGROUND:Recent studies have tested the hypothesis that preventive pulmonary vein isolation (PVI) at time of atrial flutter ablation in patients who have not had atrial fibrillation (AF) will reduce future incidence of AF. OBJECTIVE:To model relative procedural costs, risks, and benefits of sequential versus combine...

journal_title：Heart rhythm

authors： Gula LJ,Skanes AC,Klein GJ,Jenkyn KB,Redfearn DP,Manlucu J,Roberts JD,Yee R,Tang AS,Leong-Sit P

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:The prognostic significance of the clinical presentation of atrial fibrillation (AF) is poorly defined. OBJECTIVE:The purpose of this study was to determine the frequency, associations, and prognostic impact of different clinical presentations of new-onset AF. METHODS:One thousand patients with incident AF...

journal_title：Heart rhythm

authors： Siontis KC,Gersh BJ,Killian JM,Noseworthy PA,McCabe P,Weston SA,Roger VL,Chamberlain AM

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Early repolarization syndrome (ERS) is associated with polymorphic ventricular tachycardia (PVT) and ventricular fibrillation, leading to sudden cardiac death. OBJECTIVE:The present study tests the hypothesis that the transient outward potassium current (Ito)-blocking effect of phosphodiesterase-3 (PDE-3) i...

journal_title：Heart rhythm

authors： Patocskai B,Barajas-Martinez H,Hu D,Gurabi Z,Koncz I,Antzelevitch C

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Transesophageal echocardiography (TEE) is recommended in patients undergoing atrial fibrillation (AF) ablation, but use of this strategy is variable. OBJECTIVE:To evaluate whether TEE is necessary before AF ablation in patients treated with novel oral anticoagulants (NOACs). METHODS:We performed a prospect...

journal_title：Heart rhythm

authors： Di Biase L,Briceno DF,Trivedi C,Mohanty S,Gianni C,Burkhardt JD,Mohanty P,Bai R,Gunda S,Horton R,Bailey S,Sanchez JE,Al-Ahmad A,Hranitzky P,Gallinghouse GJ,Reddy YM,Zagrodzky J,Hongo R,Beheiry S,Lakkireddy D,Natal

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Cardiac arrest may result from seemingly innocuous medications that do not necessarily have cardiac indications. The best-known example is the drug-induced long QT syndrome. A less known but not necessarily less important form of drug-induced proarrhythmia is the drug-induced Brugada syndrome. OBJECTIVE:The...

journal_title：Heart rhythm

authors： Konigstein M,Rosso R,Topaz G,Postema PG,Friedensohn L,Heller K,Zeltser D,Belhassen B,Adler A,Viskin S

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Atrial tachycardia (AT) may develop after biatrial surgical ablation of atrial fibrillation. However, the mechanism has not been determined in detail. OBJECTIVE:We aimed to determine the mechanism and treatment of postoperative AT following biatrial surgical ablation in relation to the design and durability...

journal_title：Heart rhythm

authors： Takahashi K,Miyauchi Y,Hayashi M,Iwasaki YK,Yodogawa K,Tsuboi I,Hayashi H,Oka E,Ito Hagiwara K,Fujimoto Y,Shimizu W

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:The human ether-à-go-go-related gene (hERG 1a) potassium channel is critical for cardiac repolarization. hERG 1b, another variant subunit, co-assembles with hERG 1a, modulates channel biophysical properties and plays an important role in repolarization. Mutations of hERG 1a lead to type 2 long QT syndrome (L...

journal_title：Heart rhythm

authors： Puckerin A,Aromolaran KA,Chang DD,Zukin RS,Colecraft HM,Boutjdir M,Aromolaran AS

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Epicardial implantable cardioverter-defibrillator (ICD) placement in infants, children, and patients with complex cardiac anatomy requires an open surgical thoracotomy and is associated with increased pain, longer length of stay, and higher cost. OBJECTIVE:The purpose of this study was to compare an open su...

journal_title：Heart rhythm

authors： Clark BC,Davis TD,El-Sayed Ahmed MM,McCarter R,Ishibashi N,Jordan CP,Kane TD,Kim PCW,Krieger A,Nath DS,Opfermann JD,Berul CI

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Although consensus documents on catheter and surgical ablation of atrial fibrillation (AF) suggest a uniform "blanking period" of 3 months, recent evidence suggested that early recurrences of atrial tachyarrhythmias (ERATs) are strongly associated with late recurrences (LRs), especially if ERATs occurred in ...

journal_title：Heart rhythm

authors： Mugnai G,de Asmundis C,Hünük B,Ströker E,Velagic V,Moran D,Ruggiero D,Hacioglu E,Poelaert J,Verborgh C,Umbrain V,Beckers S,Coutino-Moreno HE,Takarada K,Brugada P,Chierchia GB

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Detection of atrial repolarization waves free of far-field signal contamination by ventricular activation would allow investigation of atrial electrophysiology and factors that influence susceptibility to atrial tachycardia and atrial fibrillation (AF). OBJECTIVE:The purpose of this study was to identify me...

journal_title：Heart rhythm

authors： Verrier RL,Fuller H,Justo F,Nearing BD,Rajamani S,Belardinelli L

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Recurrent atrial tachyarrhythmias occur as a result of residual atrial arrhythmogenic substrates after atrial fibrillation (AF) ablation. In patients with AF, electrograms with reduced amplitudes indicate diseased myocardium. OBJECTIVE:The purpose of this study was to investigate the association between the...

journal_title：Heart rhythm

authors： Masuda M,Fujita M,Iida O,Okamoto S,Ishihara T,Nanto K,Kanda T,Shiraki T,Sunaga A,Matsuda Y,Uematsu M

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Vernakalant inhibits several potassium currents and causes a rate- and voltage-dependent inhibition of the sodium current. OBJECTIVE:The aim of this study was to evaluate the antiarrhythmic mechanism of vernakalant in normal and electrically remodeled atria. METHODS:Fourteen goats were instrumented with el...

journal_title：Heart rhythm

authors： van Hunnik A,Lau DH,Zeemering S,Kuiper M,Verheule S,Schotten U

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Several mammalian species display distinct biophysical properties between atrial and ventricular voltage-gated sodium current (INa); however, the potential mechanism behind this phenomenon is unknown. OBJECTIVE:The purpose of this study was to investigate the potential molecular identities of the different ...

journal_title：Heart rhythm

authors： Chen KH,Xu XH,Sun HY,Du XL,Liu H,Yang L,Xiao GS,Wang Y,Jin MW,Li GR

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Heterogeneity of depolarization and repolarization underlies the development of lethal arrhythmias. OBJECTIVE:We investigated whether quantification of spatial depolarization and repolarization heterogeneity identifies individuals at risk for sudden cardiac death (SCD). METHODS:Spatial R-, J-, and T-wave h...

journal_title：Heart rhythm

authors： Kenttä TV,Nearing BD,Porthan K,Tikkanen JT,Viitasalo M,Nieminen MS,Salomaa V,Oikarinen L,Jula A,Kontula K,Newton-Cheh C,Huikuri HV,Verrier RL

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:The extent of left atrial (LA) late gadolinium enhancement (LGE), as a surrogate for fibrosis, has been associated with atrial fibrillation (AF) recurrence after catheter ablation. Furthermore, there is ex vivo evidence that islands of fibrosis may anchor fibrillatory rotors. OBJECTIVE:The purpose of this s...

journal_title：Heart rhythm

authors： Chrispin J,Gucuk Ipek E,Zahid S,Prakosa A,Habibi M,Spragg D,Marine JE,Ashikaga H,Rickard J,Trayanova NA,Zimmerman SL,Zipunnikov V,Berger RD,Calkins H,Nazarian S

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Autonomic regulation therapy (ART) with chronic vagus nerve stimulation improves ventricular function in patients with chronic heart failure, but its effects on quantitative T-wave alternans (TWA), ventricular tachycardia (VT), baroreflex sensitivity, and autonomic tone remained unknown. OBJECTIVE:Effects o...

journal_title：Heart rhythm

authors： Libbus I,Nearing BD,Amurthur B,KenKnight BH,Verrier RL

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Hypokalemia and hyponatremia increase the occurrence of atrial fibrillation. Sinoatrial nodes (SANs) and pulmonary veins (PVs) play a critical role in the pathophysiology of atrial fibrillation. OBJECTIVE:The purpose of this study was to evaluate whether electrolyte disturbances with low concentrations of p...

journal_title：Heart rhythm

authors： Lu YY,Cheng CC,Chen YC,Lin YK,Chen SA,Chen YJ

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:New approaches to ablation of atrial fibrillation (AF) include focal impulse and rotor modulation (FIRM). Studies of this technology with short-term follow-up have shown favorable outcomes. OBJECTIVE:The purpose of this study was to characterize the long-term results of FIRM ablation in a cohort of patients...

journal_title：Heart rhythm

authors： Buch E,Share M,Tung R,Benharash P,Sharma P,Koneru J,Mandapati R,Ellenbogen KA,Shivkumar K

更新日期：2016-03-01 00:00:00

abstract：:The autonomic nervous system is known to play a significant role in the genesis and maintenance of arrhythmias. Neuromodulation, mostly designed to increase the parasympathetic tone and suppress the sympathetic tone, has become an emerging therapeutic strategy for the treatment of arrhythmias. Emerging therapeutic app...

journal_title：Heart rhythm

authors： Hou Y,Zhou Q,Po SS

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Cardiac resynchronization therapy defibrillator can terminate ventricular tachycardia (VT) and fast VT (FVT) via antitachycardia pacing (ATP). OBJECTIVES:We evaluated efficacy and safety of ATP, whether ATP induces ventricular arrhythmias after inappropriate ATP or atrial fibrillation (AF) after appropriate...

journal_title：Heart rhythm

authors： Landolina M,Lunati M,Boriani G,Pietro Ricci R,Proclemer A,Facchin D,Rordorf R,Morani G,Maines M,Gasparini G,Molon G,Turrini P,Gasparini M,ClinicalService cardiological centers.

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Selective inhibitors of Kv1.5 channels are being developed for the treatment of atrial fibrillation (AF). OBJECTIVES:The purpose of this study was to investigate the effects of the highly selective Kv1.5 inhibitor XEN-D0103 on human atrial action potentials (APs) at high excitation rates and to assess safet...

journal_title：Heart rhythm

authors： Ford J,Milnes J,El Haou S,Wettwer E,Loose S,Matschke K,Tyl B,Round P,Ravens U

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Therapeutic hypothermia (TH) may increase the susceptibility to ventricular arrhythmias by decreasing ventricular conduction velocity (CV) and facilitating arrhythmogenic spatially discordant alternans (SDA). OBJECTIVE:The purpose of this study was to test the hypothesis that rotigaptide, a gap junction enh...

journal_title：Heart rhythm

authors： Hsieh YC,Lin JC,Hung CY,Li CH,Lin SF,Yeh HI,Huang JL,Lo CP,Haugan K,Larsen BD,Wu TJ

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:The failure to identify a successful target site for catheter ablation despite extensive endocardial and epicardial mapping is a common feature for an intramural site of origin of a ventricular arrhythmia. OBJECTIVE:The purpose of this study was to assess whether transient suppression of premature ventricul...

journal_title：Heart rhythm

authors： Yokokawa M,Morady F,Bogun F

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Ventricular fibrillation (VF) is induced during implantable cardioverter-defibrillator (ICD) implantation to ensure that the ICD will sense, detect, and defibrillate VF. ICD implant guidelines state that the amplitude of the sinus rhythm R wave recorded from the ventricular electrogram should have amplitude ...

journal_title：Heart rhythm

authors： Ruetz LL,Koehler JL,Brown ML,Jackson TE,Belk P,Swerdlow CD

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Premature ventricular complex (PVC) ablation has been shown to improve left ventricular ejection fraction (LVEF) and New York Heart Association functional class in patients with left ventricular dysfunction. Both are considered key variables in predicting risk of sudden cardiac death. OBJECTIVE:The objectiv...

journal_title：Heart rhythm

authors： Penela D,Acosta J,Aguinaga L,Tercedor L,Ordoñez A,Fernández-Armenta J,Andreu D,Sánchez-Millán PJ,Cabanelas N,Tolosana JM,Vassanelli F,Cabrera M,Korshunov V,Sitges M,Brugada J,Mont L,Berruezo A

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Pacing in the right ventricle can cause a variety of detrimental effects, including atrial tachyarrhythmias (atrial tachycardia [AT]/atrial fibrillation [AF]). OBJECTIVE:The purpose of this study was to evaluate the incidence and predictors of persistent AT/AF in patients with long-term exposure to ventricu...

journal_title：Heart rhythm

authors： Ricci RP,Botto GL,Bénézet JM,Nielsen JC,De Roy L,Piot O,Quesada A,Quaglione R,Vaccari D,Mangoni L,Grammatico A,Kozák M,PreFER MVP Investigators.

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Left atrial (LA) low-voltage areas (LVAs) are frequently observed in patients with atrial fibrillation (AF) and may predict AF recurrence after catheter ablation. OBJECTIVE:The aim of this study was to develop and validate a clinical tool to identify LVAs that are associated with AF recurrence after pulmona...

journal_title：Heart rhythm

authors： Kosiuk J,Dinov B,Kornej J,Acou WJ,Schönbauer R,Fiedler L,Buchta P,Myrda K,Gąsior M,Poloński L,Kircher S,Arya A,Sommer P,Bollmann A,Hindricks G,Rolf S

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Prior studies have reported that more than 20% of implantable cardioverter-defibrillator (ICD) implantations in the United States do not adhere to trial-based criteria. OBJECTIVE:We sought to investigate the patient characteristics associated with not meeting the inclusion criteria of the clinical trials th...

journal_title：Heart rhythm

authors： Kaiser DW,Tsai V,Heidenreich PA,Goldstein MK,Wang Y,Curtis J,Turakhia MP,National Cardiovascular Data Registry.

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Hyperthyroidism is a known reversible cause of atrial fibrillation (AF). However, some patients remain in AF despite restoration of euthyroid status. OBJECTIVE:The purpose of this study was to compare the electrophysiologic characteristics and long-term ablation outcome in AF patients with and without histo...

journal_title：Heart rhythm

authors： Wongcharoen W,Lin YJ,Chang SL,Lo LW,Hu YF,Chung FP,Chong E,Chao TF,Tuan TC,Chang YT,Lin CY,Liao JN,Lin YC,Chen YY,Chen SA

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Indications for pulmonary vein isolation for the treatment of atrial fibrillation (AF) have expanded over the years. OBJECTIVE:We aimed to describe trends in demographic and clinical characteristics of patients undergoing ablation, with a particular focus on sex differences. METHODS:Patients who underwent ...

journal_title：Heart rhythm

authors： Avgil Tsadok M,Gagnon J,Joza J,Behlouli H,Verma A,Essebag V,Pilote L

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Data on inappropriate implantable cardioverter-defibrillator (ICD) therapy and effects of programming by heart rate are lacking. OBJECTIVE:We aimed to characterize inappropriate ICD therapy and assess the effects of novel programming by heart rate. METHODS:Incidence and causes of inappropriate therapy by h...

journal_title：Heart rhythm

authors： Kutyifa V,Daubert JP,Olshansky B,Huang DT,Zhang C,Ruwald AC,McNitt S,Zareba W,Moss AJ,Schuger C

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Pulmonary vein isolation (PVI) is a central procedure for the treatment of paroxysmal atrial fibrillation (PAF). However, in patients with PAF and structural atrial disease, PVI may fail and cause progressive atrial remodeling, often leading to persistent/permanent atrial fibrillation. OBJECTIVE:We performe...

journal_title：Heart rhythm

authors： Faustino M,Pizzi C,Agricola T,Xhyheri B,Costa GM,Flacco ME,Capasso L,Cicolini G,Di Girolamo E,Leonzio L,Manzoli L

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Only a few studies on the cephalic vein cutdown technique for pacemaker lead implantation in children weighing ≤10 kg have been reported even though the procedure is widely accepted in adults. OBJECTIVE:The purpose of this study was to prove that cephalic vein cutdown for pacemaker lead implantation is a re...

journal_title：Heart rhythm

authors： Kircanski B,Vasic D,Savic D,Stojanov P

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Initiation of reentrant ventricular tachycardia (VT) involves complex interactions between front and tail of the activation wave. Recent experimental work has identified the time interval between S2 repolarization proximal to a line of functional block and S2 activation at the adjacent distal side as a criti...

journal_title：Heart rhythm

authors： Child N,Bishop MJ,Hanson B,Coronel R,Opthof T,Boukens BJ,Walton RD,Efimov IR,Bostock J,Hill Y,Rinaldi CA,Razavi R,Gill J,Taggart P

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Watchman and Lariat left atrial appendage (LAA) occlusion devices are associated with LAA leaks postdeployment. OBJECTIVE:The purpose of this study was to compare the incidence, characteristics, and clinical significance of these leaks. METHODS:We performed a multicenter prospective observational study of ...

journal_title：Heart rhythm

authors： Pillarisetti J,Reddy YM,Gunda S,Swarup V,Lee R,Rasekh A,Horton R,Massumi A,Cheng J,Bartus K,Badhwar N,Han F,Atkins D,Bommana S,Earnest M,Nath J,Ferrell R,Bormann S,Dawn B,Di Biase L,Mansour M,Natale A,Lakkired

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Atrioventricular nodal reentrant tachycardia (AVNRT) may coexist with Brugada syndrome (BrS). OBJECTIVES:The present study was designed to determine the prevalence of drug-induced type 1 Brugada ECG pattern (concealed BrS) in patients presenting with clinical spontaneous AVNRT and to investigate their elect...

journal_title：Heart rhythm

authors： Hasdemir C,Payzin S,Kocabas U,Sahin H,Yildirim N,Alp A,Aydin M,Pfeiffer R,Burashnikov E,Wu Y,Antzelevitch C

更新日期：2015-07-01 00:00:00

abstract：:We present an update on clinical and electrophysiological criteria used for the differential diagnosis of regular supraventricular tachycardias. Although several electrocardiographic clues may assist in the differential diagnosis, this is usually accomplished at electrophysiology study, and most often, the differentia...

journal_title：Heart rhythm

authors： Katritsis DG,Josephson ME

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Limited data exist regarding the outcome of atrial fibrillation (AF) surgery and catheter ablation in patients with hypertrophic cardiomyopathy (HCM). OBJECTIVE:The purpose of this study was to evaluate the safety and efficacy of nonpharmacologic treatment of AF in HCM. METHODS:One hundred forty-seven pati...

journal_title：Heart rhythm

authors： Bassiouny M,Lindsay BD,Lever H,Saliba W,Klein A,Banna M,Abraham J,Shao M,Rickard J,Kanj M,Tchou P,Dresing T,Baranowski B,Bhargava M,Callahan T,Tarakji K,Cantillon D,Hussein A,Marc Gillinov A,Smedira NG,Wazni O

更新日期：2015-07-01 00:00:00

abstract：:Antitachycardia pacing (ATP) strategies represent safe, effective, and painless therapy for ventricular tachyarrhythmias, with a large body of clinical evidence supporting their routine use in both primary and secondary implantable cardioverter-defibrillator recipients. This article details the evidence supporting the...

journal_title：Heart rhythm

authors： Cantillon DJ,Wilkoff BL

更新日期：2015-06-01 00:00:00

abstract：:Cardiac resynchronization therapy (CRT) is an electrical treatment of heart failure with reduced ejection fraction and wide QRS. It aims to correct the electrical dyssynchrony present in 30% to 50% of patients in this population. Dyssynchrony results in widening of the QRS complex on the electrocardiogram (ECG). CRT w...

journal_title：Heart rhythm

authors： Eschalier R,Ploux S,Ritter P,Haïssaguerre M,Ellenbogen KA,Bordachar P

更新日期：2015-05-01 00:00:00